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Zydus Lifesciences Entecavir 1 mg Tablets Recalled for Impurity Degradation Issues (2025)

Zydus Pharmaceuticals USA Inc. recalls Entecavir tablets after FDA enforcement reports impurity/degradation failures. The recall affects 4,440 bottles distributed nationwide. Providers and patients should stop use and seek guidance from a healthcare professional.

Official notice

Source-backed recall notice

No product image was available from the source feed.

Official source
FDA DRUG
Recall date
September 4, 2025
Status
ACTIVE
Severity
8/10

Quick Facts at a Glance

Recall Date
September 4, 2025
Hazard Level
HIGH
Brands
Zydus Pharmaceuticals USA Inc., Entecavir, Zydus Lifesciences Ltd.
Category
Health & Personal Care
Sold At
Unknown
Geographic Scope
1 states
At-Risk Groups
GENERAL, PREGNANT, PETS

What to Do Now

Use this page like a recall checklist: verify the product first, then act on the official remedy.

Immediate steps

  1. 1Stop using the product until you confirm whether it is included in the recall.
  2. 2Compare the product label, model number, UPC, color, size, and purchase location against the identifiers below.
  3. 3Follow the official remedy from FDA - Drug Safety; save photos, receipts, labels, and correspondence before contacting the company.
  4. 4If the product could harm a child, older adult, pet, or patient, move it out of reach immediately.

Check these identifiers

Brand
Zydus Pharmaceuticals USA Inc., Entecavir, Zydus Lifesciences Ltd.
Product type
Entecavir Tablets
Model numbers
Lot E309377, Exp 11/30/2025
UPC codes
68382-920, 68382-921, 68382-920-06, 68382-920-16, 68382-920-01, 68382-920-30, 68382-920-77, 68382-921-06 +4 more
Sizes
30 Tablets
Sold at
Unknown
Where affected
ALL

Recall Timeline

Key dates and source checks for this recall record.

  1. Recall announced

    September 4, 2025

  2. Reported by FDA DRUG

    September 24, 2025

  3. RecallRadar source check

    April 18, 2026

  4. Consumer action

    Use the official remedy and keep documentation.

Hazard Information

Failed Impurity/Degradation Specifications

What You Should Do

Consumers and healthcare providers should stop using this product immediately. Contact Zydus Pharmaceuticals (USA) Inc or your healthcare provider for guidance. Notification method: N/A

About This Product

Entecavir tablets are an antiviral used to treat hepatitis B. They are prescription-only and require medical supervision.

Why This Is Dangerous

Impurity or degradation can affect drug purity and potency, potentially compromising treatment efficacy.

Industry Context

This recall is not part of a broader industry pattern at this time.

Real-World Impact

Consumers and healthcare providers should stop use and consult a clinician for alternatives; no injuries reported in the data.

Practical Guidance

How to identify if yours is affected

  1. Locate bottle with NDC 68382-921-06
  2. Check Lot E309377 and Exp 11/30/2025
  3. Verify 30-tablet packaging and Rx Only designation

Where to find product info

NDC on bottle, packaging insert, and the FDA recall page linked in notices

What timeline to expect

Refunds/replacements typically processed within several weeks after confirmation

If the manufacturer is unresponsive

  • Document all communications
  • Escalate to FDA consumer complaint if necessary
  • Consult healthcare provider for interim treatment options

How to prevent similar issues

  • Verify NDC before dispensing medications
  • Maintain inventory controls to isolate recalled lots
  • Monitor FDA recall updates for new information

Documentation advice

Keep bottle packaging, recall notice, and correspondence with supplier for records

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Product Details

Product: Entecavir Tablets, USP 1 mg, 30 Tablets. Manufacturer: Zydus Lifesciences Ltd., Ahmedabad, India. Distributor: Zydus Pharmaceuticals (USA) Inc., Pennington, NJ 08534. NDC: 68382-921-06. Lot: E309377. Expiration: 11/30/2025. Quantity: 4,440 bottles. Sold nationwide in the U.S.

Reported Incidents

No specific incidents or injuries are reported in the provided data.

Key Facts

  • Distributed nationwide in the U.S.
  • High hazard level

Safety Guide

Not sure what to do next? Our guide walks you through the process step by step.

Read: What to Do When You Find a Recalled Product

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Safety Assessment

Risk LevelHIGH
Severity Score
8/ 10
Affected Groups
GENERALPREGNANTPETS
Injury Types
POISONINGOTHER

Product Details

Model Numbers
Lot E309377
Exp 11/30/2025
UPC Codes
68382-920
68382-921
68382-920-06
+9 more
Affected States
ALL
Report Date
September 24, 2025
Source Agency
FDA - Drug Safety
Recall Status
ACTIVE

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