HIGHFDA DRUG

Zydus Chlorpromazine Hydrochloride 10 mg Tablets Recalled for Nitrosamine Impurity (2025)

Zydus Lifesciences and Zydus Pharmaceuticals US recall Chlorpromazine Hydrochloride Tablets, 10 mg, 100-count bottles sold nationwide in the United States after detecting an impurity above acceptable intake. The impurity is N-Nitroso Desmethyl Chlorpromazine. Consumers should stop using the product immediately and contact the manufacturer for guidance.

Official notice

Source-backed recall notice

No product image was available from the source feed.

Official source
FDA DRUG
Recall date
September 3, 2025
Status
ACTIVE
Severity
8/10

Quick Facts at a Glance

Recall Date
September 3, 2025
Hazard Level
HIGH
Brands
Chlorpromazine Hydrochloride, Zydus Lifesciences, Zydus Pharmaceuticals
Category
Health & Personal Care
Sold At
Multiple Retailers
Geographic Scope
1 states
At-Risk Groups
GENERAL

What to Do Now

Use this page like a recall checklist: verify the product first, then act on the official remedy.

Immediate steps

  1. 1Stop using the product until you confirm whether it is included in the recall.
  2. 2Compare the product label, model number, UPC, color, size, and purchase location against the identifiers below.
  3. 3Follow the official remedy from FDA - Drug Safety; save photos, receipts, labels, and correspondence before contacting the company.
  4. 4If the product could harm a child, older adult, pet, or patient, move it out of reach immediately.

Check these identifiers

Brand
Chlorpromazine Hydrochloride, Zydus Lifesciences, Zydus Pharmaceuticals
Product type
Chlorpromazine Hydrochloride Tablets 10 mg
Model numbers
Z403012, Z406657
UPC codes
70710-1129, 70710-1130, 70710-1131, 70710-1132, 70710-1133, 70710-1129-1, 70710-1129-2, 70710-1129-4 +7 more
Sizes
100-count bottle
Sold at
Multiple Retailers
Where affected
ALL

Recall Timeline

Key dates and source checks for this recall record.

  1. Recall announced

    September 3, 2025

  2. Reported by FDA DRUG

    September 17, 2025

  3. RecallRadar source check

    April 18, 2026

  4. Consumer action

    Use the official remedy and keep documentation.

Hazard Information

CGMP Deviations: presence of N-Nitroso Desmethyl Chlorpromazine above the recommended acceptable intake limit

What You Should Do

Consumers and healthcare providers should stop using this product immediately. Contact Zydus Pharmaceuticals (USA) Inc or your healthcare provider for guidance. Notification method: N/A

About This Product

Chlorpromazine hydrochloride is an antipsychotic medication used to treat certain psychiatric conditions. The 10 mg tablets come in 100-count Rx bottles distributed in the U.S. by Zydus Pharmaceuticals USA.

Why This Is Dangerous

An impurity, N-Nitroso Desmethyl Chlorpromazine, was detected at levels above the acceptable intake limit during CGMP testing. Long-term exposure carries potential health risks.

Industry Context

This recall is not described as part of a broader industry pattern.

Real-World Impact

Patients currently taking this medication may need medical guidance to discuss alternatives. No injuries have been reported to date; exposure to the impurity remains a safety concern.

Practical Guidance

How to identify if yours is affected

  1. Check the bottle label for NDC 70710-1129-1.
  2. Look for Lot numbers Z403012 or Z406657.
  3. Verify expiration dates 30-Apr-2026 or 30-Nov-2026.

Where to find product info

FDA recall notice (D-0630-2025) and product labeling. See https://www.accessdata.fda.gov/scripts/enforcement/enforce_rpt-Product-Tabs.cfm?recall_number=D-0630-2025

What timeline to expect

Refunds or replacements, if offered, typically take weeks after submission. Follow physician guidance.

If the manufacturer is unresponsive

  • File a complaint with the FDA recall process
  • Consult your pharmacist for alternatives
  • Keep records of all communications and notices.

How to prevent similar issues

  • Verify CGMP compliance before distributing drug products and check impurity testing results.
  • Always check NDC and lot codes when sourcing medications.
  • Discuss any medication substitutions with a healthcare professional before making changes.

Documentation advice

Keep the recall notice, bottle label, NDC, lot numbers, and expiration dates. Record all communications with the manufacturer and pharmacy.

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Product Details

NDC 70710-1129-1; 100-count bottles; Rx only; Manufactured by Zydus Lifesciences Ltd., Baddi, India; Distributed by Zydus Pharmaceuticals (USA) Inc., Pennington, NJ; Sold nationwide in USA; Recall date 2025-09-03; FDA status Active; Lots Z403012 (Exp 30-04-2026) and Z406657 (Exp 30-11-2026)

Reported Incidents

No injuries or incidents have been reported.

Key Facts

  • Lot numbers Z403012 and Z406657
  • Exp 30-Apr-2026 and 30-Nov-2026
  • Manufactured in India; distributed in the USA

Safety Guide

Not sure what to do next? Our guide walks you through the process step by step.

Read: What to Do When You Find a Recalled Product

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Safety Assessment

Risk LevelHIGH
Severity Score
8/ 10
Affected Groups
GENERAL
Injury Types
POISONING

Product Classification

Product Details

Model Numbers
Z403012
Z406657
UPC Codes
70710-1129
70710-1130
70710-1131
+12 more
Affected States
ALL
Report Date
September 17, 2025
Source Agency
FDA - Drug Safety
Recall Status
ACTIVE

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