HIGHFDA DRUG

Zydus Lifesciences Chlorpromazine Hydrochloride Tablets Recall 100-Count Bottles (2025)

Zydus Lifesciences Ltd. recalled chlorpromazine hydrochloride tablets nationwide in the United States after tests found N-Nitroso Desmethyl Chlorpromazine above the acceptable intake limit. The issue involves CGMP deviations in manufacturing at the India facility and distribution by Zydus Pharmaceuticals (USA) Inc., Pennington, NJ. Healthcare providers and patients should stop using the product, 0

Official notice

Source-backed recall notice

No product image was available from the source feed.

Official source
FDA DRUG
Recall date
September 3, 2025
Status
ACTIVE
Severity
8/10

Quick Facts at a Glance

Recall Date
September 3, 2025
Hazard Level
HIGH
Brand
Zydus Lifesciences
Category
Health & Personal Care
Sold At
Multiple Retailers
Geographic Scope
1 states
At-Risk Groups
GENERAL

What to Do Now

Use this page like a recall checklist: verify the product first, then act on the official remedy.

Immediate steps

  1. 1Stop using the product until you confirm whether it is included in the recall.
  2. 2Compare the product label, model number, UPC, color, size, and purchase location against the identifiers below.
  3. 3Follow the official remedy from FDA - Drug Safety; save photos, receipts, labels, and correspondence before contacting the company.
  4. 4If the product could harm a child, older adult, pet, or patient, move it out of reach immediately.

Check these identifiers

Brand
Zydus Lifesciences
Product type
Chlorpromazine hydrochloride tablets
Model numbers
Z306327, Z306748, Z401154, Z403738, Z405645
UPC codes
70710-1129, 70710-1130, 70710-1131, 70710-1132, 70710-1133, 70710-1129-1, 70710-1129-2, 70710-1129-4 +7 more
Sizes
50 mg, 100-count bottle
Sold at
Multiple Retailers
Where affected
ALL

Recall Timeline

Key dates and source checks for this recall record.

  1. Recall announced

    September 3, 2025

  2. Reported by FDA DRUG

    September 17, 2025

  3. RecallRadar source check

    April 18, 2026

  4. Consumer action

    Use the official remedy and keep documentation.

Hazard Information

CGMP Deviations: presence of N-Nitroso Desmethyl Chlorpromazine above the recommended acceptable intake limit

What You Should Do

Consumers and healthcare providers should stop using this product immediately. Contact Zydus Pharmaceuticals (USA) Inc or your healthcare provider for guidance. Notification method: N/A

About This Product

Chlorpromazine hydrochloride is an antipsychotic medication used to treat certain psychiatric conditions. It is distributed as Rx-only tablets and requires medical supervision.

Why This Is Dangerous

The recall centers on CGMP deviations that led to the detection of an impurity, N-Nitroso Desmethyl Chlorpromazine, above acceptable intake limits. Consumers should stop use immediately unless advised otherwise by a healthcare provider.

Industry Context

This recall is not described as part of a broader industry pattern in the notice.

Real-World Impact

Patients with the affected product may be exposed to higher impurity levels. There is an immediate safety concern, and providers should assess alternatives as needed.

Practical Guidance

How to identify if yours is affected

  1. Identify the bottle by the NDC 70710-1131-1.
  2. Check model numbers on the bottle or packaging: Z306327, Z306748, Z401154, Z403738, Z405645.
  3. If in doubt, contact the distributor for confirmation

Where to find product info

NDC is printed on the bottle label; packaging and Rx labels list the model numbers and lot codes.

What timeline to expect

The recall notice does not specify a refund or replacement timeline.

If the manufacturer is unresponsive

  • File a complaint with FDA if the company is unresponsive
  • Consult your healthcare provider for guidance on alternatives

How to prevent similar issues

  • Always verify NDC and model numbers before using Rx drugs
  • Consult a pharmacist or physician before switching medications
  • Stay informed via official FDA recall notices

Documentation advice

Keep the recall notice, bottle label, and any correspondence with the manufacturer or healthcare providers. Photograph the label and store a digital copy of the notice.

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Product Details

Model numbers: Z306327, Z306748, Z401154, Z403738, Z405645. NDC: 70710-1131-1. Sold nationwide in the USA. Manufactured by Zydus Lifesciences Ltd., Baddi, India. Distributed by Zydus Pharmaceuticals (USA) Inc., Pennington, NJ 08534. Rx only. Price: Unknown. Sold as 50 mg, 100-count bottles.

Reported Incidents

No injuries or incidents have been reported.

Key Facts

  • Nationwide distribution in the United States.
  • Manufactured in Baddi, India; distributed by Zydus Pharmaceuticals (USA) Inc., Pennington, NJ.
  • Hazard: CGMP deviations with N-Nitroso Desmethyl Chlorpromazine above acceptable limits.
  • Hazard level: HIGH; no reported injuries.

Safety Guide

Not sure what to do next? Our guide walks you through the process step by step.

Read: What to Do When You Find a Recalled Product

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Safety Assessment

Risk LevelHIGH
Severity Score
8/ 10
Affected Groups
GENERAL
Injury Types
POISONING

Product Details

Model Numbers
Z306327
Z306748
Z401154
Z403738
Z405645
UPC Codes
70710-1129
70710-1130
70710-1131
+12 more
Affected States
ALL
Report Date
September 17, 2025
Source Agency
FDA - Drug Safety
Recall Status
ACTIVE

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