HIGHFDA DRUG

Zydus Entacavir Recall 600 Bottles Over Impurity Degradation Issue (2025)

Zydus Lifesciences and Zydus Pharmaceuticals USA recall 600 bottles of Entacavir 1 mg tablets distributed nationwide in the United States. An out-of-specification organic impurity triggered the recall. Stop use immediately and contact a healthcare provider or Zydus for guidance.

Official notice

Source-backed recall notice

No product image was available from the source feed.

Official source
FDA DRUG
Recall date
September 24, 2025
Status
ACTIVE
Severity
8/10

Quick Facts at a Glance

Recall Date
September 24, 2025
Hazard Level
HIGH
Brands
Entacavir, Zydus Pharmaceuticals USA Inc.
Category
Health & Personal Care
Sold At
Unknown
Geographic Scope
1 states
At-Risk Groups
GENERAL, PREGNANT, PETS

What to Do Now

Use this page like a recall checklist: verify the product first, then act on the official remedy.

Immediate steps

  1. 1Stop using the product until you confirm whether it is included in the recall.
  2. 2Compare the product label, model number, UPC, color, size, and purchase location against the identifiers below.
  3. 3Follow the official remedy from FDA - Drug Safety; save photos, receipts, labels, and correspondence before contacting the company.
  4. 4If the product could harm a child, older adult, pet, or patient, move it out of reach immediately.

Check these identifiers

Brand
Entacavir, Zydus Pharmaceuticals USA Inc.
Product type
Antiviral Tablet
Model numbers
LotE409309
UPC codes
68382-920, 68382-921, 68382-920-06, 68382-920-16, 68382-920-01, 68382-920-30, 68382-920-77, 68382-921-06 +4 more
Sold at
Unknown
Where affected
ALL

Recall Timeline

Key dates and source checks for this recall record.

  1. Recall announced

    September 24, 2025

  2. Reported by FDA DRUG

    October 8, 2025

  3. RecallRadar source check

    April 18, 2026

  4. Consumer action

    Use the official remedy and keep documentation.

Hazard Information

Failed impurity/degradation specifications:Out of Specification result for an individual organic impurity

What You Should Do

Consumers and healthcare providers should stop using this product immediately. Contact Zydus Pharmaceuticals (USA) Inc or your healthcare provider for guidance. Notification method: Letter

About This Product

Entacavir is an antiviral used to treat hepatitis B infection. It is prescribed by physicians and distributed to patients nationwide.

Why This Is Dangerous

The product failed impurity/degradation specifications, indicating an organic impurity beyond acceptable limits, which could pose safety risks if consumed.

Industry Context

This recall is not indicated as part of a broader industry pattern in the provided data.

Real-World Impact

No incidents reported in the notice, but patients must stop use and consult their clinician to determine next steps.

Practical Guidance

How to identify if yours is affected

  1. Verify lot number E409309 on the bottle
  2. Check expiration date 12/31/2026
  3. Confirm NDC 68382-921-06 on packaging

Where to find product info

Label shows lot number, expiration date, NDC code, and manufacturer information

What timeline to expect

Refunds or replacements processed per company policy after notification; no firm timeline provided

If the manufacturer is unresponsive

  • Escalate with FDA recall portal or consumer protection office
  • Seek guidance from healthcare provider while pursuing replacement

How to prevent similar issues

  • Always verify lot numbers and expiration dates before dispensing medications
  • Report any adverse events to FDA MedWatch
  • Review drug recall notices from FDA for antiviral medications

Documentation advice

Keep recall notice, packaging, receipts, and communication logs with manufacturer for records

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Product Details

Model numbers: Lot# E409309. Expiration: 12/31/2026. Quantity: 600 bottles. Sold nationwide in the USA. Manufactured by Zydus Lifesciences Ltd., Ahmedabad, India. Distributed by Zydus Pharmaceuticals USA Inc., Pennington, NJ 08534. NDC 68382-921-06.

Reported Incidents

No consumer injury or adverse event data provided in the recall notice.

Key Facts

  • Distributed nationwide in USA
  • High hazard level

Safety Guide

Not sure what to do next? Our guide walks you through the process step by step.

Read: What to Do When You Find a Recalled Product

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Safety Assessment

Risk LevelHIGH
Severity Score
8/ 10
Affected Groups
GENERALPREGNANTPETS
Injury Types
POISONINGOTHER

Product Details

Model Numbers
LotE409309
UPC Codes
68382-920
68382-921
68382-920-06
+9 more
Affected States
ALL
Report Date
October 8, 2025
Source Agency
FDA - Drug Safety
Recall Status
ACTIVE

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